Rabbit anti Proprotein convertase subtilisin/kexin type 9 (PCSK9) antibody LDLR-binding epitope blocking

Many awards

The Blocking Peptides we offer receive many awards.

Best practices

Systematic production of Activating Antibody ensuring their high quality.

Big trust

To this day, many customers have trusted us and our Antibody products.


100 μg

Catalog no.



304 EUR



Antibody's reacts with


Antibody is raised in




Protein number

see ncbi

French translation




Antibody's specificity

No Data Available

Relevant references

no information yet


Primary Antibodies

Latin name

Oryctolagus cuniculus

Antibody come from

Influenza B virions, Yamagata strain.

Antibody's reacts with these species

This antibody doesn't cross react with other species


Western Blot, Functional epitope reported to block PCSK9-LDLR interaction. ELISA


You can block the antibody by the specific target amino acid sequence of peptide.

Antibody's suited for

Immunofluorescence: 1:500_x000B_Optimal concentration should be evaluated by serial dilutions.

Antigen-antibody binding interaction

Rabbit anti Proprotein convertase subtilisin/kexin type 9 (PCSK9) antibody LDLR-binding epitope blocking Antibody

Other description

Supplied as a liquid in PBS, pH 7.5, 0.1% sodium azide, before the addition of glycerol to 40%. Ammonium Sulfate Precipitation


If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.


This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.


This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.


Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.

Long description

This anitbody is made to an epitope that is reported to block the PCSK9-LDLR (low density lipoprotein receptor) interaction. PCSK9 binds to the EGF-A domain of the LDLR and signals LDLR degradation. Reduced LDLR levels result in decreased LDL (low density lipid) metabolism leading to hypercholesterolemia. _x000B__x000B_Additioanlly, PCSK9 may be implicated in the differentiation of cortical neurons and may also play a role in cholesterol homeostasis. Defects in PCSK9 gene are the cause of familial hypercholesterolemia 3 (FH3). The protein is thought to play a central role in cholesterol homeostais